

A vaccination failure occurs when the chickens do not develop suitable antibody titer levels and/or are susceptible to a field disease outbreak. Therefore, an updated review has been thoroughly developed in order to highlight the importance of detecting and solving the major vaccination failures in commercial chickens.
A vaccination failure occurs when the chickens do not develop suitable antibody titer levels and/or are susceptible to a field disease outbreak. Therefore, an updated review has been thoroughly developed in order to highlight the importance of detecting and solving the major vaccination failures in commercial chickens.
Authors:
MOHAMED FAIZAL ABDUL-CAREEM
Assistant Professor (virology) at the University of Calgary (Canada) since 2010. He is diplomate of American College of Poultry Veterinarians (ACPV) and American College of Veterinary Microbiologists (ACVM).
Key Features:
➜ Written by an expert with a wide experience in this field.
➜ Numerous graphic resources included.
➜ Small and easy-to-handle format.
Table of Contents:
1. Introduction
Significance of poultry infectious diseases
Control options for poultry infectious diseases
General definition of vaccination
History of poultry vaccines and vaccination
Economic benefits of vaccination
2. Types of poultry vaccines
Killed vaccines
Live attenuated vaccines
DNA vaccines
Recombinant vaccines
3. Vaccination techniques
Spray vaccination
Drinking water vaccination
Parenteral routes
In ovo vaccination
4. Vaccine-mediated immune
responses
Mechanisms of induction of
vaccine-mediated immune responses
5. Evaluation of vaccine efficacy
Monitoring vaccine take
Monitoring antibody response
Monitoring protection
Table of contents
6. Causes of vaccination failures
General definition of vaccination failure
Evolution of pathogens
Poor cross protection between serotypes,
pathotypes and strains
of the same pathogen
Maternal antibody interference
Early exposure to pathogens
Exposure to heavy pathogen loads
Immune suppressive conditions
of the host
Uneven vaccine uptake
Improper vaccine storage and handling
during vaccination
7. Field examples of
vaccination failures
Marek’s disease
Infectious bronchitis
Infectious bursal disease
Newcastle disease
Infectious laryngotracheitis
Avian influenza
Fowlpox
8. Overcoming vaccination
failures in poultry flocks
References
Data sheet
Specific References